What people should be aware of is how important is the state of mind.
People take these drugs as they are superheroes and can handle them like cigarettes. 
Even marijuana is something to handle curely. 
If you are not in a peacefull and relaxed state of mind you should never take any drug. Reason why I didn't take Salvia Divinorum for the second time while in Amsterdam. A naive friend of mine did even tho I seemed a little scared and sad. It was the worst experience of his life. 

Anyway, I believe these drugs are shit. Many say they take it just to become "more consciousness". There are many other ways to become more consciousness and maybe the first step is considering to not take any drugs.